I posted a review on this one months ago but it seems to have fallen into a blackhole and I have no backup. This was a very difficult book for me due to the prose style. I just found it a little rambling, unclear and unfocussed. I kept losing track of where the current scene is taking place and which characters are present, not to mention what exactly was happening. In all fairness this probably my own failure and not the author's, his prose style just does not resonate with me.
That said this book is generally critically well received and there are many ingenious concepts in this book which feature a truly inscrutable alien, several highly modified human characters and a scientifically convincing vampire. If you find the synopsis of this book (not part of this review!) interesting there is no reason not to give it a try it as it is available as a free e-book here